Innovations in primate interneuron repertoire

We report single-nucleus transcriptomes from brain regions in 5 species: mice: Frontal Cortex, V1, Hippocampus, Striatum; common marmoset: 7 neocortical regions, Hippocampus, Striatum (Nucleus Accumbens, Caudate, Putamen); rhesus macaque: Prefrontal Cortex, V1; human: Prefrontal Cortex, V1, Striatum (Caudate); ferret: Prefrontal Cortex, V1, Striatum Single-nucleus suspensions were made from frozen brain tissue and sampled with Drop-seq or 10X 3' v3 chemistry.本研究报道了5个物种的多个脑区的单细胞核转录组（single-nucleus transcriptome）数据，涉及的物种及对应脑区如下：小鼠：额叶皮层、V1、海马体、纹状体；普通狨猴：7个新皮层脑区、海马体、纹状体（伏隔核、尾状核、壳核）；恒河猴：前额叶皮层、V1；人类：前额叶皮层、V1、纹状体（尾状核）；雪貂：前额叶皮层、V1、纹状体。实验采用冰冻脑组织制备单细胞核悬液，并通过Drop-seq或10X 3' v3化学技术完成测序采样。