iPS derived melanocyte precursor cells. iPS derived melanocyte precursor cells

We found distinct and self-renewal cell linages that could differentiate into melanocytes, named melanocyte precursor cells (MPCs) in which MPCs revealed drastically differntiation to authentic melanocytes by a small amount of GSK3β inhibitor in about seven days. Comparing MPCs ,iPSCs and melanocytes, we showed wnt sigal systems in differentiation to melanocytes. Overall design: We extracted total RNA from iPSCs, MPCs,induced melanocytes from iPSCs and human epidermal melanocytes and hybridized them to Agilent gene expression microarrays.