Development of gene expression signatures for HCV infection. Development of gene expression signatures for HCV infection

To further elucidate the gene expression profile alterations induced by HCV infection, we have employed the Arraystar Human LncRNA Microarray V3.0 as a discovery platform to identify genes associated with HCV infection. Human hepatocellular carcinoma cell line Huh7.5.1 was infected with HCVcc for 6 h. The gene expression pattern of HCVcc-infected Huh7.5.1 was compared with that of uninfected Huh7.5.1 to identify the differentially expressed genes induced by HCV infection. Overall design: Gene expression profiling analysis of RNA-seq data for Huh7.5.1 cells infected with HCVcc for 6 h and uninfected Huh7.5.1 cells.