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Homo sapiens Epigenomics

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP116363
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We report scCAT-seq, a technique for simultaneous assay of chromatin accessibility and transcriptome within the same single cell. By applying scCAT-seq to different cancer cell types, we identified trans-factors as bridges linking accessibility variation of cis-regulatory elements to cell-type-specific gene expression across single cells. We further characterized subpopulations within cancer cells and uncovered the regulatory clues that drive transcriptional heterogeneity.
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2020-05-20
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