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Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=255c8d5cd92c1585c20802e62e8cb79b
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资源简介:
Neural progenitors derived from human pluripotent stem cells (hPSCs) develop into electrophysiologically active neurons at heterogeneous rates, which can confound disease-relevant discoveries in neurology and psychiatry. The goal of this study was to resolve the diversity of functional states of hPSC-derived neurons in vitro by combining patch clamping with morphological and RNA-sequencing analysis of single neurons (Patch-seq).
提供机构:
South Australian Health and Medical Research Institute (SAHMRI)
创建时间:
2022-02-20
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