Pseudomonas-mediated arginine deprivation downregulates RBM39 and inhibits triple-negative breast cancer progression

This dataset presents distinct microbial communities and metabolic signatures between tumor and non-tumor tissues. Key findings highlight the role of Pseudomonas spp. in arginine depletion within the tumor microenvironment (TME), leading to RBM39 downregulation, cancer cell apoptosis, and tumor suppression. The dataset includes analyzed microbial composition, metabolic profiles, and functional evaluations of Pseudomonas spp. through cell biology assays and in vivo tumor-bearing mouse models.