Time resolved study of globular and membrane protein crystals with 1000 Hz X-ray pulses

We will use different types of injection systems like Fixed target, LCP (Liquid cubic phase) as Mixing injectors. These systems will be used with known successful media from recent FEL beamtimes as with new or modified media to adapt for the 1000 Hz probe system. We will provide photosystem I crystals, which we can now make to uniform size between 5 and 100 um. As second membrane protein the Cytochrome c Oxidase(CcO) can be provided. For globular proteins we can provide Phycocyanin C from cyanobacteria , overexpressed Nendo U protein from Covid-19 virus with RNA or analogs, BRD 3-1 protein domain with potential ligand