Structure of NUDT15 in complex with inhibitor TH8321
收藏Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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Structure of NUDT15 in complex with inhibitor TH8321 Descriptor: 2-azanyl-9-cyclohexyl-8-(2-methoxyphenyl)-3~{H}-purine-6-thione, MAGNESIUM ION, Nucleotide triphosphate diphosphatase NUDT15 Authors: Rehling, D, Zhang, S.M, Helleday, T, Stenmark, P. Deposit date: 2020-10-14 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.35 Å) Cite: NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir. Cell Chem Biol, 28, 2021
创建时间:
2020-10-14



