Crystal structure of E.coli thymidylate synthase with dUMP and the BGC 945 inhibitor
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Crystal structure of E.coli thymidylate synthase with dUMP and the BGC 945 inhibitor Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2'-deoxy-5'-uridylic acid, MAGNESIUM ION, ... Authors: Tochowicz, A, Finer-Moore, J, Stroud, R.M. Deposit date: 2013-01-16 Release date: 2013-12-25 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.752 Å) Cite: Development and Binding Mode Assessment of N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-gamma-glutamyl-d-glutamic Acid (BGC 945), a Novel Thymidylate Synthase Inhibitor That Targets Tumor Cells. J.Med.Chem., 56, 2013
创建时间：
2013-01-16
