3D DNA-FISH microscopy images related to Fig.S5C, Fig.S5D (Number of associated file: 7) Manuscript: Lleres, David; Moindrot, Benoit; Noordermeer, Daan; Feil, Robert (2019), “CTCF modulates all
While, transcriptional and epigenetic changes associated senescence processes are well studied, the 3D chromatin changes associated with it remains elusive. In this study, we have generated genome wid
HiCUP is a pipeline for processing sequence data generated by Hi-C, a technique used to investigate the three-dimensional organisation of a genome. The pipeline maps data to a specified reference geno
The CRISPR system is widely used in genome editing for biomedical research. Here, using either dual paired Cas9D10A nickases or paired Cas9 nuclease we characterise unintended larger deletions at on-t
