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Dynamic Kinetic Resolution Enabled Synthesis of Planar and Central Chiral Ferrocenes

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NIAID Data Ecosystem2026-05-10 收录
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https://figshare.com/articles/dataset/Dynamic_Kinetic_Resolution_Enabled_Synthesis_of_Planar_and_Central_Chiral_Ferrocenes/31941418
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Ferrocene scaffolds with planar and central chirality are privileged motifs in enantioselective catalysis. Herein, we disclose a dynamic kinetic resolution (DKR) strategy in which chiral allenes enable consecutive axial-to-planar and axial-to-central chirality transfer, allowing the construction of planar and central chiral ferrocenes in up to 80% yield and 96% ee.
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2026-04-06
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