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A novel paracrine induction of RNA granules by feline calicivirus

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE171655
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In this study we are examining the paracrine effect induced by feline calicivirus (FCV) infection on stress granule (SG) accumulation. We provided an understanding of paracrine granules function and specificity through their affinity purification followed RNAseq to systematically analyse their RNA content. We purified in triplicate a granule enriched fraction from GFP-G3BP1 U2OS cells treated (and not) with the virus free supernatant. The RNA was then purified, sequenced and compared to the total RNA.
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2022-05-11
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