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Discovery of a Potent and Selective mPGES-1 Inhibitor for the Treatment of Pain

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Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Discovery of a Potent and Selective mPGES-1 Inhibitor for the Treatment of Pain Descriptor: (2-hydroxyethoxy)acetaldehyde, 2-(difluoromethyl)-5-{[(2-methylpropanoyl)amino]methyl}-N-{5-methyl-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-2-yl}pyridine-3-carboxamide, GLUTATHIONE, ... Authors: Fisher, M.J, Schiffler, M.A, Kuklish, S.L, Antonysamy, S, Luz, J.G. Deposit date: 2015-05-29 Release date: 2016-04-13 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors. J.Med.Chem., 59, 2016
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2015-05-29
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