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EZH2 inhibition sensitizes MYC-high medulloblastoma cancers to PARP inhibition by regulating NUPR1-mediated DNA repair

Name: EZH2 inhibition sensitizes MYC-high medulloblastoma cancers to PARP inhibition by regulating NUPR1-mediated DNA repair
Creator: Children's Hospital of Fudan University
Published: 2026-04-09T12:25:45+08:00

Mendeley Data2026-04-09 收录

母细胞瘤靶向治疗

DNA修复

数据链接：

https://data.mendeley.com/datasets/cfnsrt63g7 数据链接链接失效反馈

官方服务：

资源简介：

The differentially expressed genes from the RNA-seq

应用场景：

提供机构：

Children's Hospital of Fudan University

蛋白质晶体

DNA修复

Crystal structure of human RECQL5 helicase APO form. Descriptor: ATP-dependent DNA helicase Q5, ZINC ION Authors: Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edw

Protein Data Bank Japan2024-05-08 更新70

WILD-TYPE URACIL-DNA GLYCOSYLASE BOUND TO URACIL-CONTAINING DNA

DNA修复

结构生物学

WILD-TYPE URACIL-DNA GLYCOSYLASE BOUND TO URACIL-CONTAINING DNA Descriptor: 5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*(D1P)P*AP*TP*CP*TP*T)-3', URACIL, ... Authors: Parikh, S.S, Mol

Protein Data Bank Japan2023-08-02 更新40

DataSheet_1_Chaperonin containing TCP-1 (CCT/TRiC) is a novel therapeutic and diagnostic target for neuroblastoma.pdf

母细胞瘤靶向治疗

神经母细胞瘤诊断标志物

Chaperonin containing TCP1 (CCT/TRiC) is a multi-subunit protein folding complex that enables the cancer phenotype to emerge from the mutational landscape that drives oncogenesis. We and others linked

NIAID Data Ecosystem30

Structure of human DNA polymerase beta complexed with dzA as the template base in a 1-nucleotide gapped DNA

DNA修复

聚合酶结构

Structure of human DNA polymerase beta complexed with dzA as the template base in a 1-nucleotide gapped DNA Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*(4DU)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*G

Protein Data Bank Japan2023-10-18 更新60

Homologous and Nonhomologous Recombination Resulting in Deletion: Effects of p53 Status, Microhomology, and Repetitive DNA Length and Orientation

基因组稳定性

DNA修复

Repetitive DNA elements frequently are precursors to chromosomal deletions in prokaryotes and lower eukaryotes. However, little is known about the relationship between repeated sequences and deletion

PubMed Central30

EZH2 inhibition sensitizes MYC-high medulloblastoma cancers to PARP inhibition by regulating NUPR1-mediated DNA repair

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