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PKA C3 immunoprecipitation mass spectrometry

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NIAID Data Ecosystem2026-05-02 收录
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Toxoplasma gondii possesses three protein kinase A (PKA) orthologs. PKA C3 has been implicated as a negative regulator of transformation from the acute stage tachyzoites to the chronic stage bradyzoites. We performed immunoprecipitation of PKA C3 and identified interaction partners by mass spectrometry. The apicomplexan-specific AGC kinase SPARK emerged as a strong interaction partner of PKA C3.

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2024-07-12
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