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Analysis of miRNAs in MCF7 cells regulated by LSD1

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218200
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Lysine specific demethylase 1 (LSD1) is an important histone demethylase that mediates metastasis in luminal breast cancer. Thus, the characterization of miRNAs in MCF7 cells regulated by LSD1 is imperative in clarifying intercellular signaling. miRNA-seq in scrambled control siRNAs transfected MCF7 cells (NC), LSD1-specific siRNAs transfected MCF7 (KD), MCF7 cells transfected with LSD1-specific siRNAs and LSD1 rescue plasmid (RE). Each cell type have 3 biological replicates.
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2024-03-13
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