Histopathological alterations can be seen after IP MPTP injection, but not oral application.
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(A) Representative pictures of the striatum after anti-tyrosine hydroxylase (TH) staining and quantification (B). Mice were investigated two days after MPTP treatment. Reduction of TH positive fibers is only seen in IP treated animals (pMethods) or with one (1×) single dose of 60 mg/kg. Scale bars: 50 µm. n = 3, striatal fibers were analyzed in a field of 45×45 µm. Error bars represent SEM.
创建时间：
2016-02-24
