Single-cell RNAseq data of cortical organoids derived from patients with NARS mutations and controls
收藏NIAID Data Ecosystem2026-04-25 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP230327
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资源简介：
Cortical organoids generated from iPSCs derived from microcephalic patients and matched controls were collected at differentiation day 52, combined and dissociated into single cells. 10X Genomics Chromium system and Single Cell 3' Reagent Kits V2 were used to generate cDNA and sequencing libraries. The mutations were: A homozygous missense mutation in NARS (c.50G>A, p.T1M) and A compound heterozygous mutations (c.[1067A>C]; [203dup], p. Asp256Ala, p. Met9Aspfs*). Each library was sequenced using the Illumina Hiseq4000 PE100bp in Rapid Run Mode.
创建时间：
2020-05-26
