Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold
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Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold Descriptor: CARBONATE ION, TPSB2 protein, {(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone Authors: Zhang, Y, Colonna, C, Michot, N. Deposit date: 2011-12-22 Release date: 2012-03-14 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.09 Å) Cite: A beta-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity Bioorg.Med.Chem.Lett., 22, 2012
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2011-12-22
