Polygenic architecture informs potential vulnerability to drug-induced liver injury. Polygenic architecture informs potential vulnerability to drug-induced liver injury

药物安全性预测

Drug-Induced-Liver-Injury (DILI) is a leading cause of termination in drug development programs and removal of drugs from the market because of inability to identify potential patients prior to clinic

NIAID Data Ecosystem90

Contains the following files.

药物性肝损伤遗传学

结核病基因组学

Table A. Information of primers and probes. Table B. IL-6, STAT3 and HSPA1L Polymorphisms in Patients with and without ATDH (unmatched case-control study). Table C. ORs and 95% CIs for ATDH in relatio

NIAID Data Ecosystem70

Distribution of genotypes in patients with and without anti-TB drug-induced hepatitis.

药物性肝损伤遗传学

基因型表型关联分析

aconditional logistic regression model analysis. bDom, dominant model; Rec, recessive model; Add, additive mode.

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