CD8+ T cells can be reprogrammed for better persistence and robust effector function in TME. By performing an in vivo pooled CRISPR-Cas9 mutagenesis screening of metabolism-associated factors, we iden

NIAID Data Ecosystem00

Data Sheet 1_A CD47 antibody with minimized erythrocyte and thrombocyte toxicities.docx

肿瘤免疫治疗

CD47抗体

IntroductionBlockade of the CD47/SIRPa axis has emerged as a promising approach to enhance macrophage-mediated anti-tumor activities in cancer immunotherapy. However, the clinical application of early

NIAID Data Ecosystem00

DataSheet4_A systematic pan-cancer analysis reveals the clinical prognosis and immunotherapy value of C-X3-C motif ligand 1 (CX3CL1).ZIP

癌症生物标志物

肿瘤免疫治疗

It is now widely known that C-X3-C motif ligand 1 (CX3CL1) plays an essential part in the process of regulating pro-inflammatory cells migration across a wide range of inflammatory disorders, includin

NIAID Data Ecosystem00

Co-cultures between hgp100-pulsed splenocytes with Pmel mouse CD8 T cells treated with human recombinant AOAH protein or vehicle (10% glycerol PBS)

肿瘤免疫治疗

AOAH蛋白靶点验证

Secreted proteins are central mediators of intercellular communications and can serve as therapeutic targets in diverse diseases. The ~1903 human genes encoding secreted proteins are difficult to stud

NIAID Data Ecosystem00