Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP104298
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资源简介：
We identified that Drosophila FoxA transcription Fork Head (FKH) function is necessary for reduced insulin signalling and rapamycin induced longevity. Furthermore, we determined that FKH function in the gut tissue alone is sufficient to extend lifespan. We carried out RNA-sequencing in gut tissue on controls (daGS;InRDN>GFP- RNAi) and reduced insulin signalling background upon control RNAi (daGS;InRDN>GFPRNAi +RU486) and upon FKH RNAi (daGS;InRDN>FKH- RNAi +RU486). InR-DN stock used: K1409A.
创建时间：
2023-10-13
