Baseline and Treatment Characteristics of the Subjects in Safety Sample.

* tPA = tissue plasminogen activator** OCSP = Oxfordshire Community Stroke Project stroke classification (TACS = total anterior circulation syndrome; PACS = partial anterior circulation syndrome; LACS = lacunar syndrome; POCS = posterior circulation syndrome)¶BP = blood pressure; IV = intravenous; ECG = electrocardiogram† Race and ethnic group were self-reported.‡ The National Institutes of Health Stroke Scale (NIHSS) is a 42-point scale that quantifies neurological deficits in 11 categories, with 0 indicating normal function without deficits, and higher scores indicating greater severities of deficit.§ The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) uses computed tomography to assess 10 regions of the brain; a score of 1 indicates a normal region and 0 indicates a region showing signs of ischemia. Total scores range from 10 (no evidence of early ischemia) to 0 (all 10 regions of the affected hemisphere show early ischemic changes).Baseline and Treatment Characteristics of the Subjects in Safety Sample.