Samples of human containing Bacteria and Archaea microorganisms Raw sequence reads

This is a randomized controlled clinical trial with the objective of investigating the effect of Brazilian nuts (BN) associated to a calorie-restricted diet on health. Regular Brazilian nuts have been associated to better outcomes in health. BN provides nutrients, lipids and bio compounds that could improve satiety and weight loss, microbiota modulation, especially monounsaturated fatty acids, selenium, flavanols and minerals. However, we have no evidence of greater benefits of BN intake, compared to a healthy calorie-restricted diet free of nuts. This study aimed clarify the impact of BN intake in a context of calorie-restricted diet on intestinal microbiota and permeability, and mechanisms related (satiety, inflammation, oxidative stress).