首页/数据集/Tetraspanin 3 is Required for the Development and Propagation of Acute Myelogenous Leukemia

Tetraspanin 3 is Required for the Development and Propagation of Acute Myelogenous Leukemia

ChEBI2015-06-04 更新2026-07-12 收录

白血病发病机制

肿瘤分子靶点

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-69512 数据链接链接失效反馈

官方服务：

资源简介：

Tetraspanin 3 is Required for the Development and Propagation of Acute Myelogenous Leukemia

应用场景：

创建时间：

2015-06-04

白血病发病机制

血液肿瘤分子病理学

The translocation t(10,11)(p13;q14) resulting in the formation of the CALM/AF10 fusion gene is involved in various hematological malignancies including acute myeloid leukemia, T-cell acute lymphoblast

NIAID Data Ecosystem40

Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia

白血病发病机制

造血干细胞表观遗传学

RUNX1 is among the most frequently mutated genes in human leukemia, and the loss or dominant-negative suppression of RUNX1 function is found in myelodysplastic syndrome and acute myeloid leukemia (AML

NIAID Data Ecosystem20

Cre-recombinase expression cooperates with FLT3ITD/ITD to induce acute myeloid leukemia [RNASeq_SclCre_BM]

肿瘤动物模型

白血病发病机制

Animal models offer a valuable tool to recapitulate genetically defined subtypes of AML, and to assess the potential of compound mutations and clonal evolution during disease progression. This is of u

NIAID Data Ecosystem20

SNP data of MPD/MPN samples. Homo sapiens

骨髓增殖性肿瘤基因组学

白血病发病机制

Philadelphia-chromosome negative myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia and primary myelofibrosis show an inherent tendency for transformation into

NIAID Data Ecosystem20

Influence of MLL/ENL expression on murine bone marrow cells with a conditional Mef2c knockout or a Mef2c rescue

白血病发病机制

血液肿瘤分子病理学

Acute myelogenous leukemia (AML) is driven by leukemic stem cells (LSC) generated by mutations that confer (or maintain) self-renewal potential coupled to an aberrant differentiation program. Using re

NIAID Data Ecosystem20

Tetraspanin 3 is Required for the Development and Propagation of Acute Myelogenous Leukemia

资源简介：

相关数据集