High-Intensity Personalized Temporal Interference Targeting Striatum Enhances Functional Stability in the Sensorimotor Network

The raw dataset comprises resting-state functional magnetic resonance imaging (rs-fMRI) data from 28 healthy participants collected in a crossover, double-blind, randomized controlled trial. Data include pre- and during-stimulation fMRI scans for both temporal interference (TI) stimulation (10 mA, Δf=20 Hz, 20 minutes targeting right striatum) and sham conditions using personalized electrode montages. Dynamic functional connectivity was computed using sliding-window correlation analysis, with primary outcome measures including voxel-wise functional stability quantified by Kendall's concordance coefficient across the whole brain and seed-based dynamic functional connectivity variability measured as standard deviation across temporal windows for the right striatum.