Cardiac hypertrophic response

Integrated schematic of the more extensively characterized intracellular signal-transduction pathways that coordinate the cardiac hypertrophic response. During development and in response to physiological stimuli or pathological insults, the heart undergoes hypertrophic enlargement, which is characterized by an increase in the size of individual cardiac myocytes. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP2795 CPTAC Assay Portal]

该描述呈现了协调心脏肥大反应的详细细胞内信号转导途径的综合示意图。在发育过程中，以及对生理刺激或病理损伤的响应下，心脏经历肥大扩张，其特征为单个心肌细胞体积的增加。该途径上的蛋白质拥有针对的检测方法，可通过[https://assays.cancer.gov/available_assays?wp_id=WP2795 CPTAC检测门户]获取。