Crystal structure of hcv ns5b polymerase in complex with compound 12
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Crystal structure of hcv ns5b polymerase in complex with compound 12 Descriptor: 6-[3-(pyridin-2-yl)-2-(trifluoromethyl)phenoxy]-1-(2,4,6-trifluorobenzyl)quinazolin-4(1H)-one, GLYCEROL, Genome polyprotein, ... Authors: Coulombe, R. Deposit date: 2013-03-24 Release date: 2013-07-03 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular Dynamics Simulations and Structure-Based Rational Design Lead to Allosteric HCV NS5B Polymerase Thumb Pocket 2 Inhibitor with Picomolar Cellular Replicon Potency. J.Med.Chem., 57, 2014
创建时间：
2013-03-24
