Crystal structure of human CLK1 in complex with pyrido[3,4-g]quinazoline derivative ZW31 (compound 14)
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Crystal structure of human CLK1 in complex with pyrido[3,4-g]quinazoline derivative ZW31 (compound 14) Descriptor: Dual specificity protein kinase CLK1, GLYCEROL, PHOSPHATE ION, ... Authors: Chaikuad, A, Esvan, Y.J, Zeinyeh, W, Boibessot, T, Nauton, L, Thery, V, Loaec, N, Meijer, L, Giraud, F, Moreau, P, Anizon, F, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2016-03-29 Release date: 2016-05-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structure. Eur.J.Med.Chem., 118, 2016
创建时间：
2016-03-29
