CCL17 promotes colitis-associated tumorigenesis dependent on the microbiota. CCL17 promotes colitis-associated tumorigenesis dependent on the microbiota

• CCL17 expression is increased in colitis-associated colon tumors • Single-housed CCL17-deficient mice develop fewer tumors dependent on the microbiota • Reduced tumor numbers coincide with increased apoptosis during tumor initiation Overall design: Sorted cells from tumors from CCL17 ko mice cohoused with control mice or CCL17 ko mice separately housed after AOM DSS treatment