Single cell RNA sequencing mapping the adult human esophagus in vivo and in vitro

Despite advances and innovations in characterization of adult esophageal epithelial stem cells, there is still a gap in reliable in vitro methods that closely recapitulate human cell behavior in a physiological-in vivo relevant fashion. Therefore, in this data set we set up to bench mark a detailed single-cell atlas of adult human esophagus with matched in vitro model for long term culture.