Data from: Clinical management and mortality among COVID-19 cases in sub-Saharan Africa: a retrospective study from Burkina Faso and simulated case analysis.
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https://datadryad.org/dataset/doi:10.5061/dryad.1rn8pk0r4
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资源简介:
Absolute numbers of COVID-19 cases and deaths reported to date in the
sub-Saharan Africa (SSA) region have been relatively low. As a result,
there has been limited investigation into deceased cases in the region, as
well as the impacts of different case management strategies. We detail
demographic, epidemiological, and clinical information derived from
publicly available information on deceased cases in SSA and, for cases in
Burkina Faso, from aggregate records at the Center Hospitalier
Universitaire de Tengandogo. Logistic regression was conducted on a
synthetic case population to evaluate the adjusted odds of survival for
patients receiving oxygen therapy or convalescent plasma, based on
therapeutic effectiveness observed for other respiratory illnesses. Across
SSA, deceased cases have been predominantly male and over 50 years of age.
After adjustment for sex, age, and underlying conditions, the odds of
mortality among cases in the synthetic population not receiving oxygen
therapy was significantly higher than those receiving oxygen (OR: 2.07;
95%CI: 1.56-2.75). Cases receiving convalescent plasma had 50% reduced
odds of mortality (95%CI: 0.24-0.93). Investment in sustainable oxygen
therapy could reduce COVID-19 deaths in SSA. Ongoing investigation into
convalescent plasma is warranted, as data on its effectiveness
specifically in treating COVID-19 becomes available.
提供机构:
Dryad
创建时间:
2020-06-23



