Latent HIV infection disrupts cell-intrinsic innate immunity [scRNA-seq]. Latent HIV infection disrupts cell-intrinsic innate immunity [scRNA-seq]

Single Cell RNA Sequencing in Primary CD4 T-Cells infected with HIV, suppressed with ART, and treated with IFNb Overall design: Primary CD4 T cells from human donors cultured with homeostatic cytokines then mock-infected or infected with NanoLuc HIV, supressed with ART for 7 days and then treated with media or IFNB for 8 hours