Exploring the Mechanisms of Leonurine in Attenuating PCOS: Focus on Gut Microbiota and Short-Chain Fatty Acids

NIAID Data Ecosystem2026-05-02 收录

多囊卵巢综合征机制

肠道菌群代谢干预

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资源简介：

Depleting the gut microbiota by antibiotic treatment in Control + ABX and DHEA + ABX group

创建时间：

2025-02-04

Comprehensive molecular features of polycystic ovary syndrome revealed by transcriptome analysis of oocytes and cumulus cells. Comprehensive molecular features of polycystic ovary syndrome revealed by transcriptome analysis of oocytes and cumulus cells

多囊卵巢综合征机制

生殖细胞转录组

We aimed to elucidate the molecular features and identify causative factors for PCOS through an integrated, transcriptomic analysis of oocytes and cumulus granulosa cells (GCs) from the same patients

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Reduction of gut microbiome-derived phenyl sulfate prevents diabetic nephropathy and renal dysfunction

糖尿病机制

肠道菌群代谢干预

Diabetic nephropathy is a major cause of dialysis and prognosis is extremely unsatisfactory. Accumulation of various metabolites have been detected and several biomarkers for diabetic nephropathy have

NIAID Data Ecosystem30

Constant light exposure deteriorates gut dysbiosis and aggravates PCOS-like changes

多囊卵巢综合征机制

肠道菌群与内分泌交互

Related microbiotic mechanisms involving in develoment of PCOS

NIAID Data Ecosystem20

Intestinal flora is a key factor in insulin resistance and contribute to the development of polycystic ovary syndrome and ameliorates glucose metabolism via activation of intestinal farnesoid X receptor. PCOS and Intestinal flora (mice)

多囊卵巢综合征机制

肠道菌群调节

Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disease and was reported to be affected by the gut microbiome dysbiosis. We recruited treatment-naïve PCOS patients and hormonally

NIAID Data Ecosystem30

Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes

肠道菌群代谢干预

2型糖尿病

The intestinal microbiota plays an important role in host metabolism via production of dietary metabolites. Microbiota imbalances are linked to type 2 diabetes (T2D), but dietary modification of the m

NIAID Data Ecosystem30

Exploring the Mechanisms of Leonurine in Attenuating PCOS: Focus on Gut Microbiota and Short-Chain Fatty Acids

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