Palladium-Catalyzed Asymmetric Synthesis of Allylic Fluorides
收藏NIAID Data Ecosystem2026-03-06 收录
下载链接：
https://figshare.com/articles/dataset/Palladium_Catalyzed_Asymmetric_Synthesis_of_Allylic_Fluorides/2705128
下载链接
链接失效反馈官方服务：
资源简介：
The enantioselective fluorination of readily available cyclic allylic chlorides with AgF has been accomplished using a Pd(0) catalyst and Trost bisphosphine ligand. The reactions proceed with unprecedented ease of operation for Pd-mediated nucleophilic fluorination, allowing access to highly enantioenriched cyclic allylic fluorides that bear diverse functional groups. Evidence that supports a mechanism in which C−F bond formation occurs by an SN2-type attack of fluoride on a Pd(II)-allyl intermediate is presented.
创建时间：
2010-12-15
