Contribution of Clumping Factor B to Pathogenesis of Experimental Endocarditis due to Staphylococcus aureus
收藏PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC101814/
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资源简介:
Staphylococcus aureus Newman with an insertion mutation in clfB, the gene encoding clumping factor B, only marginally decreased infection rate (P > 0.05) in rats with experimental endocarditis. In contrast, clfB complementation on a multicopy plasmid significantly increased infectivity (P < 0.05) over the deleted mutants. Although clfB could affect endovascular infection, its importance in experimental endocarditis was limited.
提供机构:
American Society for Microbiology (ASM)



