Next Generation Sequencing of Acidosis Response in Intestinal Epithelial Cells. Next Generation Sequencing of Acidosis Response in Intestinal Epithelial Cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA648094
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Purpose: The goal of this study is to define the impact of extracellular acidosis on transcriptional regulation in intestinal epithelial cells. We identify a significant induction of CREB target genes and upregulation of several genes associated with MAPK signaling. This work provides a frame work for the identification of acidosis signaling pathway in intestinal epithelial cells Overall design: mRNA profiles of T84, human intestinal epithelial cells, treated wth pH 7.4 or 6.0 Hanks buffered saline for 3 or 6hr
创建时间：
2020-07-23
