Distribution of KIR genotype groups in patients with and without acute graft rejection.

Differences between frequencies of three genotype groups: χ2 = 6.675, df = 2, p = 0.035.Abbreviations: AA, homozygote for the killer immunoglobulin-like receptor A haplotype (for a definition of A and B haplotypes, see Introduction); AGR, acute graft rejection; BX, a group of the killer immunoglobulin-like receptor genotypes containing at least one B haplotype; as they contain different combinations of KIR genes, the presence or absence of particular genes could not been shown here; KIR, killer immunoglobulin-like receptor; KIR2DS4fl, KIR2DS4 full length gene; KIR2DS4del, KIR2DS4 22-base pair deletion variant of the KIR2DS4 gene; Pts, patients.