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Effects of the Sox17 ?50 mutation on SOX17 function in mouse embryonic liver development

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP159140
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To determine the role of specific cis-regulatory elements within the Sox17 endoderm-preferential TSS2 promoter, we generated Sox17?50 mutant animals and surveyed how this mutation altered Sox17 expression. Livers were isolated from E12.5 Sox17?50/?50 and Sox17+/+ embryos (n = 4 of each genotype), RNA isolated, and bulk RNA-Seq performed.
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2024-11-01
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