Olig2 targetome in SHH subgroup of medulloblastoma. Mus musculus
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA407111
下载链接
链接失效反馈官方服务：
资源简介：
Several basic helix-loop-helix (bHLH) transcription factors are upregulated in Sonic Hedgehog subgroup of medulloblastoma (SHH MB). Olig2, a neural bHLH transcription factor known to regulate differentiation of neural cell populations, is broadly expressed in mouse models of SHH MB. ChIP-Seq of Olig2 revealed its binding to a large number of sites near genes known to promote SHH MB tumorigenesis, suggesting a potential role for Olig2 in regulating transcriptional programme of MB. Overall design: Examination of Olig2-bound DNA in P13 Sufu;Spop double knockout and SmoM2 overexpression medulloblastoma in mice
创建时间：
2017-09-13
