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Kinetic parameters describing the interaction of PfCRTDd2 with CQ and PPQ.

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Figshare2023-06-07 更新2026-04-28 收录
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Shown are the parameters from the two best models explaining the data presented in Fig 4. Vmax, maximal velocity of drug transport; KS, dissociation constant for the PfCRT-substrate complex; β, partiality factor; α, KS interaction factor; SEM, standard error; CI, confidence interval. N, number of determinations per kinetic analysis; n, total number of oocytes. For the CQ (PPQ) kinetics: N = 35, n = 838; for the PPQ (CQ) kinetics: N = 35, n = 545.
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2023-06-07
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