Crystal structure of catalytic domain of TACE with inhibitor
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Crystal structure of catalytic domain of TACE with inhibitor Descriptor: 4-({[4-(BUT-2-YN-1-YLOXY)PHENYL]SULFONYL}METHYL)-1-[(3,5-DIMETHYLISOXAZOL-4-YL)SULFONYL]-N-HYDROXYPIPERIDINE-4-CARBOXAMIDE, ADAM 17, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ... Authors: Xu, W, Condon, J.S, Lovering, F.E. Deposit date: 2006-08-21 Release date: 2006-12-05 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Identification of potent and selective TACE inhibitors via the S1 pocket. Bioorg.Med.Chem.Lett., 17, 2007
创建时间:
2006-08-21



