Exome sequencing of senescence-accelerated mice. Mus strain:SAMP and SAMR

Senescence-accelerated mice (SAM) are inbred mice strains consisting of senescence-prone (SAMP) strains and senescence-resistant (SAMR) strains generated by an accidental intercross between the AKR/J strain and a strain of unknown origin. To identify coding-region mutations that are commonly present among the SAMP strains but absent in the SAMR strains as well as those unique for each SAM strain, we performed whole exome sequencing of 6 SAMP and 3 SAMR strains along with AKR/J and C57BL/6J strains.