Oscillating and stable promoter-enhancer loops underlie core- and clock-controlled gene expression rhythms in mouse liver

The circadian clock dynamically rewires promoter-enhancer loops in tissues to drive robust daily rhythms in gene transcription and locomoter activity. Total RNA and crosslinked genomic DNA extracted from mouse tissues during the dirunal cycle. Mouse genotype conditions include WT, Bmal1 KO, and Cry1Intron KO.