Pro-inflammatory cytokines expression with arginine or glutamine supplementation in DSS-induced colitis model.

At day 7, colonic proinflammatory cytokines production in mice treated with DSS feeding basal diet (DS), or 1.5% arginine supplementation (DS+Arg), or 2.0% arginine supplementation (DS+Gln), were detected. At day 12, colonic proinflammatory cytokines production in mice treated with DSS feeding basal diet (DS), or 0.4% arginine supplementation (DS+Arg), or 0.5% glutamine supplementation at day 12 (DS+Gln), were detected. Data are presented as mean ±SEM, n = 6, with a-c used to indicate a statistically significant difference (P<0.05, one way ANOVA method). IL: Interleukin, TNF: tumor necrosis factor.