Crystal structure of NRas-G12D in complex with GDP and compound 7
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Crystal structure of NRas-G12D in complex with GDP and compound 7 Descriptor: (4P)-4-{3-[(1R,5S,6r)-3-azabicyclo[3.1.0]hexan-6-yl]-7-fluoro-1-methyl-1H-pyrazolo[4,3-c]pyridin-6-yl}-5-ethynyl-6-fluoronaphthalen-2-ol, CITRIC ACID, GTPase NRas, ... Authors: Johnson, T.A, Cross, J.B. Deposit date: 2025-08-31 Release date: 2026-02-25 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure-Guided Development of NRAS G12D Inhibitors Based on a 5‐Azaindole Core. Acs Med.Chem.Lett., 17, 2026
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2025-08-31
