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Crystal structure of human soluble adenylyl cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate and the allosteric inhibitor LRE1

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of human soluble adenylyl cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate and the allosteric inhibitor LRE1 Descriptor: 1,2-ETHANEDIOL, 6-chloro-N~4~-cyclopropyl-N~4~-[(thiophen-2-yl)methyl]pyrimidine-2,4-diamine, ACETATE ION, ... Authors: Kleinboelting, S, Steegborn, C. Deposit date: 2016-03-18 Release date: 2016-08-17 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Nat.Chem.Biol., 12, 2016
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2016-03-18
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