Bruton's tyrosine kinase (BTK) functions in many types of immune cells and is a major chemotherapeutic target. BTK is activated at the plasma membrane and can dimerize through its pleckstrin-homology
Adenovirus E4orf4 protein has been shown to induce p53-independent, protein phosphatase 2A (PP2A)-dependent apoptosis in transformed cells. Furthermore, E4orf4 also induces toxicity in Saccharomyces c
We have developed a general method for screening randomly mutagenized expression libraries in mammalian cells by using fluorescence-activated cell sorting (FACS). The cDNA sequence of a secreted prote
