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Reference human genome samples spiked with synthetic DNA ladder

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP263079
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To demonstrate the use of the synthetic DNA ladder spike-ins in genome sequencing, we added the ladder into well-characterised reference human DNA samples (NA12878, NA24385, NA24149 and NA24143) and performed whole genome sequencing. We show how the ladder can be used as a reference to estimate technical variation and measure quantitative genetic features within and between samples.
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2020-06-09
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