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Synthesis of Quinolinones with Palladium-Catalyzed Oxidative Annulation between Acrylamides and Arynes

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NIAID Data Ecosystem2026-03-08 收录
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An unprecedented palladium-catalyzed oxidative annulation of acrylamides with benzyne precursors has been successfully developed. By using this mild “N–H activation/Heck reaction” method, a wide variety of quinolinones were conveniently prepared in one step with high efficiency.

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2016-02-14
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